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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0377c5d450d4cf967aab46b5569b3fa7188e0e569b0ec077ec330ff8acbc1a4f' 
  AND token = 'sfjDfmER9E/teEjHunx7gzCt+N+df9aYTHkVNhQJ+Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}