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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d10c817640aa99debafb830b0fe3657067091e294711bbe3b1b65aee3b6a01d' 
  AND token = 'YLqc8ZQ42ZAtP18VgmQhUOOIOMTDIRvFs4x6+pkDBkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}