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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1af71d535aefd94bed346aa996ba18ebb169c59f3b8382d84a2cfc29701838c' 
  AND token = 'p8kcQ0DDk0++vimQCf/N3tXyN5lUQOdwgUbJ3TdYf4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}