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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48caa33773581a822fa188699e089e045605ebfeb18551b63eb4339b670b0f56' 
  AND token = 'Eex5KjoSK8i/qtaxG97kgXbSZLeOxROqEFVRmH+b9UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}