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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b03fbea5e91623817a57bd5fc40bf3ed050b7d867ac10f8370a75429b7d56aa' 
  AND token = 'Wd/eFt8km8VzCVlaJSB5QN+hnLN5N4yKFWSuYAIgNic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}