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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e6a89ef8ca05d7805c1b85f95fa82577cf90b99b4e2b034d1882afd8bb1e77' 
  AND token = 'Nexmz+blt6ZlyrDdVlBZdgNr6vivnDpnpfBt5hzrnIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}