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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144eb3b3f9adbbce186b5020aa01a9d0be4d37de296384abc1ab366932e236b3' 
  AND token = 'GFTHv/X506NW9MxqLgblc4yg5iPnrZ/N8XbVa7D0mWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}