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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3bbda349d0a92175113726c89554d68d81d3815203d59a788dbb084d5f05cb0' 
  AND token = 'v4X4f+7WxOi0S49/Ehw78ibeGO3Csj3HZWRLzCUFTjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}