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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04918b5bff59857bbf5ff80608f4cc7cfd22b23fecce6100607084b60cf55cf5' 
  AND token = 'GTbOKIqnFwCY24e1eGIpHEqfjzPYiyIQg7B8FkFgQN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}