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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b423eb75aa000bda45032f37414ef8e5a7420b170279dc8cf211ffc9dc4b182' 
  AND token = '0mYn4Cb/1XNkCe5Hw8U7SPeU7fVwN6Gt/sdOXVGOliE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}