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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd87bf8303e6154c65c74d962d2e0542a7b71bcdb55237c499a0029ab0c116469' 
  AND token = 'pu3CUHUDhdCza0m/et1lwdEOsvtui8kcp2bgbCF8gWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}