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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0fb299cb6421e9513455738ee1fbaccb2301ce48f14bf8b9bfb21a8a46f8a2' 
  AND token = 'ZQ1J+iYHlGIxEOYxQOUQOAIh4rggHUCgjB5ki6HA8/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}