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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f4f94eeae2a38e8390a42a46e404f8cc664c629558642aec697b4f574a1ab9' 
  AND token = 'obGl/Bd3MfPp0nkl9/Hyrt++VpbyHMC0cgmxYNMx8UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}