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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6e6b7c0ecb8044983f2140b10f214f5ee13d719ddcb7bfd65924cfbb8c620c' 
  AND token = 'UFXoI6DuvuMJAB0gd1TqLdBVv13yal8GZHCgksWxYdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}