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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8008569ea1126ae3cd585cc86587ca6db1276eb8ca1280d3cd4522495424d5' 
  AND token = 'pb2Bqlnw9/Yza0CFAnmeg7P+y63iwYXF0O/NsXLb4UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}