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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8172887c3e07b65f4b4e75486f668a4985156b7cef36175936988de51e7cdc' 
  AND token = 'XlxVN3R2wEYagKLFI3mhaeGvGDCMSGby5xcj4Q4EhtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}