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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9272d1fd12c9c4be21ee00c012122c810d2f87bc2aac3546a6b5c81cc679a35' 
  AND token = 'nkEFzh1/XRU8PtRqHWzeleNqHopYJccQrTKbgOhhT94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}