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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a45ac5f4925c4f131ea974e5a625cb61c96d856cb4f1893f0f93b6edd13ca6e' 
  AND token = 'IcGjc0OtqmDVSGCxBVs2nnyDU2SmyOeXh8ze9vso93I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}