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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517f5f34baabbe4c59a95fe8935b9cce2b0ed8f502fb1665c4fca26d59d39d29' 
  AND token = 'uQJRBtc/bLMwY1eturjV7HX5RBPa2HvN/tt7zXXa+xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}