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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efbc4232fc96d47369f669e765f7e5618c2adec438f122a4436e0d494deed7f3' 
  AND token = 'gnhtCdvvvl9lsWeVsE7W49qktMDhNBUNtd6GcTvD+vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}