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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c29675ac4c48b1acc63171f27fad1cbddacb74e09371c50d90581b909cb3f9' 
  AND token = 'TpEDGU0skFxU5kbDO/2deT3cZ4dvP7G7kCPZzxZO6JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}