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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f53bf002ad39245806ae6802a40f02975e58e9b6f54a08adfbc38bed2bd3dca' 
  AND token = 'GW266T06sKd8tUfQ8BBZ1pS/5taW75/PIKAohnpsAj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}