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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8fc4318617e17ab24151107b35e2f7bfdd7df8b07d0d80c320de5af148d0ec' 
  AND token = '7eS0D4eoCs+edB7DHqRqJIfkH6FwWIa3lul03ic4ozI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}