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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443c33adbe44a8f11c679bc2024a973938fc30daa0aaedec752f64981349707c' 
  AND token = '85UpbsIW29kKC9zjPuTSRqtxzq0ayU41zObWzegamVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}