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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26af579fecc28e8fb80946771ab758fd01f7ea4ed1631e1ed1600de099b526b2' 
  AND token = 'HRNNQEDAxzs8+XtA+Mij/YdrsrLF9Fz+g8+n/CuBXxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}