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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a226d8819721a426107e63a8f42c0dcd15060d08f7a76bf80bb4cf610ac99a' 
  AND token = 'R6cU2J78SD8oKTQk15aNPmC89RwcA7bZzUqf9MDbp5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}