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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0042d87a6b19bc01981df0d3451fb07ffa5996006d1b587c44e05a4974ad1245' 
  AND token = 'FfzaFoY9TcTNGcWV3Qx7uYTWnUKBAO5SbUZFD/UXb7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}