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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5963ea5f449a8cd345b7f73d272a646641afc3627b8dfd518305c0ebe01cb7d5' 
  AND token = 'Mb08VqYjjMe1pjBw0om0A3xSNefGfIVC0lE0sM3lUXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}