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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd538d738e34e351030ae277ed4d9219582aed27c0859106d38d6be903851f790' 
  AND token = 'X04z1UJaS+dqGSA9cqlasZcmpq/4137mAe/PXyakLiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}