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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a234ae417f30f5073fbd149335eb3079ade89f74ceba5ffa6ae6f0cd43994566' 
  AND token = '+mbB6c7N5jsbLgeYphuSIJshNS+WcntIoXZ6XgGcS2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}