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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3b1f4916459e95545cdbfbb9d5113e5881e6713cd1bb897f6a4237cdfdf5913' 
  AND token = 'J67gJr8FZ+CpUGc1QzAknA3A0LYEZTTetZkfiZTR9LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}