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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '723157f005bf1f89884f12104153002db78435b9b3a2974ca2c1a408a6b93fad' 
  AND token = '9iWReM0snOCM+w38dhys2IlJnC5An2uTogluoHYvQNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}