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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24590bd57696f7c4977aab52c02461c3773262ffc794614088fd9278aa066d35' 
  AND token = 'tQ9V9mUxHv+DQJLQ2tNjHaAB2oCuBH0MWk7GJBcodHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}