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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec9040021a2b56baa3866c2bd9b660dbd86c9f5032d17758600595c49f9c247' 
  AND token = '1FIzWYNuEdFcDp+GY368wVnN42LHQVPi7MeWuLW/Aus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}