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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eaa16713b325a150f0f1e7726cdacbd34915ae6051b36a09e4c74a243657650' 
  AND token = 'BN1CkrT9Bko1mcxOwvYoeZOQO3Z+dKXo1DmyoqMlS9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}