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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22f2f81b6d0389881e328a6c3c15f61d1cb1229b7e5ff2e6a10bd12a5612291' 
  AND token = 'DqSDerlz1xIHyPx32e1jY0EZ/ZU6N+J0BVsF5qByAgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}