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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b25efc473e47b4cfa7c05a4c82da7c0abaaaf4b2a4e0eddfb57a16f2286e2da' 
  AND token = 'UM2KtqN5SVM2u41SJf1wenEC3KBVrOcCSY1pVkyOXGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}