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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0760c7f890d2abaf18dcc77b1aa3f2bf49da4405b0623c43482c794174fa8c50' 
  AND token = 'fIxz0QVVVOEeneyG9ReKSnheu12H4biWJNQaKlHD+IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}