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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e163f36d1d65ebf2e7a9e5f860cf064d4bf1f25e0582313c5fa7bde76e780617' 
  AND token = 'VDwOiivSVZfl991FgzrRpXS5hQ39hwuWk39SYwiMZ6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}