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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8a7fc856dbd01c04e5d67c3f1c803bcb0a477dadaadc4ee4c040365f67bbba' 
  AND token = '5PJ3Gk9/QrlccC62SWIwFCSCXpaoB1MpqD/KWtr56Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}