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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c1f76c126a0beed2b0905ebf1c109f960c9b32435d00fe8deb71732734424d' 
  AND token = 'ekULS6zNjItqTNl8dQLS7/MWVUAFXiMARJ0nsW2XZN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}