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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c0183dd29d4dab293f971a5e659da6a9c333501efb8a9c93dcaf5603ab0748' 
  AND token = 'dHlXpID0RnKsGt2TI2WDIc4FiLwPxUvPeNuHoL9HrEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}