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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e91851b34f7425b216c621b6da6a3ffa4c65ee84239de68919ca253339f1f38a' 
  AND token = '3RMTUB1crC04i/3/pVU6H4a1MLEgL8GF8bAv6RiVwuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}