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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d716b5bb206dabd1988f689bddd56ecb4a425f1b733842241c8675a2641c72' 
  AND token = 'yRtC7rxBkSSXCirAA2jDgcidiINu3hjfdT4wGyAaat0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}