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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03729b7eb56086bc368ad515e4e097b98749b09a32e14d16dd443c1152b0e8c2' 
  AND token = 'ogECPsyKIh+h58Ui8+kJ6yx+6XbnjhBAlmbKvZAtPv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}