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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e37f5f3b339e2e410e5d911cf6de2d8e55cc93c2d2d852979062088aa51fcdc' 
  AND token = 'qIRUyKqwSWnuLkGvUAMod6kZ6O2WAjmZEmMlBiN+EXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}