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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5afa1c58fe5cdfaf6aa011b348b939b76f6e19e379eb3e3fdb1015762d19cf7c' 
  AND token = 'TvP+faZL7VboUa1qtyzC5jybI+WeIh6erA/G0/PXdAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}