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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f04b6ebd1496168be1bca28b17ea6db3547b889081d5bd2f250836fe713bf8a' 
  AND token = 'aAxQZOyi6c6TCHP6HiJ5nDi5gWvyH+RWe0M9hR15yiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}