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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16c474b8f7f492f31e6b8e42d2c056d8331e12fcd23f9e020adf4f7a7575a9f' 
  AND token = '8Wh6lBPTX1pXn5IVp5vtHKwm2cu1FkdsX91Nq3h1rIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}