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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b865a32a3027eeee4c9665fd85596e18d70178bb7b363d06d74d431ff40235' 
  AND token = 'ARXM36OzwI5iPQF4AXDb6MeJZyWysyKvMsbOY3IR2I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}